Indomethacin is a powerful nonsteroidal anti-inflammatory drug (NSAID) commonly used in hospitals and clinics across South Africa for the management of pain, inflammation, and certain types of arthritis. Nurses play a crucial role in ensuring the safe administration of this medication by monitoring patient response, educating about potential side effects, and maintaining accurate dosage schedules. Understanding patient care guidelines and being alert to any adverse reactions can significantly improve outcomes and prevent complications. This guide provides a detailed overview of nursing responsibilities when administering indomethacin, including dosage management, monitoring, and patient education.

Dosage Guidelines and Administration
Nurses must strictly follow the recommended indomethacin dosage to ensure both effectiveness and patient safety. Typically, doses vary depending on the patient’s age, weight, and condition, with adults often receiving 25–50 mg two to three times daily. In hospital settings, indomethacin may be administered orally or intravenously under close supervision. Nurses should verify prescription orders, monitor renal and hepatic function, and assess patient tolerance before administration. Special care is required for elderly patients or those with pre-existing cardiovascular conditions to avoid complications. Educating patients on taking the drug with food can help minimize gastrointestinal discomfort and enhance compliance.
Monitoring for Side Effects
Regular monitoring is a key responsibility for nurses when administering indomethacin. Common side effects include nausea, heartburn, dizziness, and headache, while more severe reactions may involve gastrointestinal bleeding or kidney impairment. Nurses should conduct routine vital signs assessments, observe for signs of allergic reactions, and document any adverse effects in the patient’s chart. Prompt reporting to a physician is essential if serious symptoms occur. Patients should also be educated to immediately notify healthcare providers of any unusual symptoms, ensuring timely intervention and reducing the risk of serious complications.
Patient Education and Care Guidelines
Effective nursing care involves educating patients on proper medication use and safety precautions. Nurses should advise patients to avoid alcohol, remain hydrated, and not exceed prescribed doses. It is important to inform patients about the potential for interactions with other drugs, such as anticoagulants or other NSAIDs. Nurses should also guide patients on proper storage of indomethacin and encourage them to keep a log of their symptom relief and any side effects. By providing clear instructions and support, nurses help patients maintain adherence while minimizing health risks.
Special Considerations and Precautions
Nurses must pay special attention to patients with renal, hepatic, or cardiovascular conditions, as indomethacin may exacerbate these issues. Monitoring laboratory results, including liver enzymes and kidney function, is essential for ongoing safety. For post-operative or hospitalized patients, nurses should ensure accurate documentation of dosage times and patient response. Pregnant and breastfeeding patients require additional caution, and indomethacin should only be administered under strict medical supervision. By understanding these special precautions, nurses can provide safer, more effective patient care and prevent adverse outcomes.
| Parameter | Recommended Nursing Action | Notes |
|---|---|---|
| Oral Dosage | Administer 25–50 mg two to three times daily | Give with food or milk to reduce GI upset |
| IV Dosage | Follow physician’s prescription closely | Monitor infusion site and patient vital signs |
| Side Effects | Monitor for nausea, dizziness, GI bleeding | Report severe reactions immediately |
| Lab Monitoring | Check liver and kidney function regularly | Adjust dosage if necessary |
| Patient Education | Explain medication use, interactions, and precautions | Document counseling in patient chart |
FAQs
1. What is the main use of indomethacin?
It is primarily used for pain and inflammation relief.
2. How should nurses monitor patients?
By checking vital signs and watching for side effects.
3. Can indomethacin be taken with food?
Yes, taking it with food reduces stomach irritation.
4. Are there special precautions for elderly patients?
Yes, monitor for cardiovascular and kidney complications closely.
